Showing posts with label psilocybin. Show all posts
Showing posts with label psilocybin. Show all posts
Friday, January 1, 2010
Psilocybin
the Supreme Court recently held (Gonzales v. O Centro) that the use of hallucinogens in religious ceremonies is protected under the Religious Freedom Restoration Act and must be permitted unless there is a particularized showing of harm.
Psilocybin
The Johns Hopkins University Psilocybin and Cancer Study
Posted by The Monochromatic Knight under Entheogen, Health, Non-Ordinary States, Psychology, Science, Well-Being | Tags: Anxiety, Cancer, Depression, Psilocybin, Spirituality, Study |
[3] Comments
Anxious and/or depressed cancer patients will receive psilocybin treatment similar to that in Dr. Grob’s study, except that it includes early-stage cancer patients and a different research design. This study specifically focuses on spiritual experience facilitated by psilocybin as a healing factor in patients suffering from anxiety and/or depression secondary to their cancer diagnosis. It also includes studies of immune system responses to such spiritual experiences, so is also a study about spirituality and physical health. Subject recruiting just begun, and potential subjects can be referred to the study coordinator: See Below.
http://www.bpru.org/cancer/
Posted by The Monochromatic Knight under Entheogen, Health, Non-Ordinary States, Psychology, Science, Well-Being | Tags: Anxiety, Cancer, Depression, Psilocybin, Spirituality, Study |
[3] Comments
Anxious and/or depressed cancer patients will receive psilocybin treatment similar to that in Dr. Grob’s study, except that it includes early-stage cancer patients and a different research design. This study specifically focuses on spiritual experience facilitated by psilocybin as a healing factor in patients suffering from anxiety and/or depression secondary to their cancer diagnosis. It also includes studies of immune system responses to such spiritual experiences, so is also a study about spirituality and physical health. Subject recruiting just begun, and potential subjects can be referred to the study coordinator: See Below.
http://www.bpru.org/cancer/
psilocybin
Chemistry
Psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) is a prodrug that is converted into the pharmacologically active compound psilocin in the body by a dephosphorylation reaction.[20] This chemical reaction takes place under strongly acidic conditions, or under physiological conditions in the body, through the action of enzymes called phosphatases. Psilocybin is a tryptamine compound having a chemical structure derived from tryptophan and containing a ring configuration called an indole linked to an ethylamine substituent. It bears a close structural resemblance to the neurotransmitter serotonin (5-hydroxytryptamine). Psilocybin is a zwitterionic alkaloid that is soluble in water, moderately soluble in methanol and ethanol, and insoluble in most organic solvents. Exposure to light is detrimental to the stability of aqueous solutions of psilocybin, and will cause it to rapidly oxidize—an important consideration when using it as an analytical standard.[21] A method for the large-scale synthesis of psilocybin was reported by a Japanese group in 2003.[22]
Psilocybin (O-phosphoryl-4-hydroxy-N,N-dimethyltryptamine) is a prodrug that is converted into the pharmacologically active compound psilocin in the body by a dephosphorylation reaction.[20] This chemical reaction takes place under strongly acidic conditions, or under physiological conditions in the body, through the action of enzymes called phosphatases. Psilocybin is a tryptamine compound having a chemical structure derived from tryptophan and containing a ring configuration called an indole linked to an ethylamine substituent. It bears a close structural resemblance to the neurotransmitter serotonin (5-hydroxytryptamine). Psilocybin is a zwitterionic alkaloid that is soluble in water, moderately soluble in methanol and ethanol, and insoluble in most organic solvents. Exposure to light is detrimental to the stability of aqueous solutions of psilocybin, and will cause it to rapidly oxidize—an important consideration when using it as an analytical standard.[21] A method for the large-scale synthesis of psilocybin was reported by a Japanese group in 2003.[22]
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